Alternative Names:

Calnexin; CANX; CNX; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90;

Application:

WB IHC ICC/IF FC

Reactivity:

Human Rat

Dilution:

WB 1:1000~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200 FC 1:100

Purification:

Affinity-chromatography

Specificity:

Calnexin Antibody detects endogenous levels of Calnexin

Immunogen:

A synthesized peptide derived from human Calnexin

Description:

Calnexin is a calcium-binding protein embedded in the ER membrane that retains the newly synthesized glycoproteins inside the ER to ensure proper folding and quality control (3-5). The specificity of calnexin for a subset of glycoproteins is defined by a lectin site, which binds an early oligosaccharide intermediate on the folding glycoprotein.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.