Alternative Names:

HTRA2; HtrA-like serine protease; OMI; PARK13; PRSS25; Serine protease 25;

Application:

WB

Reactivity:

Mouse,Hamster

Dilution:

WB 1:1000

Western blot detection of HtrA2/Omi in CHO-K1,MEF and 3T3 cell lysates using HtrA2/Omi mouse mAb(dilution 1:1000).Predicted band size:49kDa.Observed band size:36kDa.

Purification:

Affinity-chromatography

Specificity:

HtrA2/Omi Mouse mAb detects endogenous levels of total HtrA2/Omi

Immunogen:

Recombinant human HtrA2/Omi protein.

Description:

Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.