Anti Active Rab7 Mouse Monoclonal Antibody
- CR-M26923
- 科博瑞生物
- 湖北省武汉市
- 现货
- 30ul
- 4800 元
- 2024-06-12 16:06:28
科博瑞（武汉）生物科技有限公司
一键申请试用
咨询
加入意向单
联系方式
- 种属
- 4800
Active Rab7 GTP [CR-M26923]
[30 µL]
| Catalog Number: CR-M26923 |
| Gene Symbol: RAB7 |
|
Description: Anti Active Rab7 Mouse Monoclonal Antibody
|
| Background: Rab7 belongs to the Rab family of small GTPases. Rab7 is located in the late endosome, lysosome, cytoplasmic vesicle, phagosome and melanosome. It is involved in the late endocytic transport and contributes to the maturation of phagosomes. |
| Immunogen: Recombinant full length protein of active Rab7 |
| Applications: IP, IHC, IF |
| Recommended Dilutions: 1 µg for ~2 mg total cellular proteins for IP 1:100 dilution for IHC, IF |
| Concentration: 1 mg/ml |
| Host: mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti active Rab7 antibody recognizes active Rab7 proteins of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Immunoprecipitation/Western blot: |
 |
Rab7 activation assay. Purified full-length Rab7 proteins were immunoprecipitated after treated with GDP (lane 1) orGTPγS (lane 2). Immunoprecipitation was done with the anti active Rab7 monoclonal antibody (Cat. No. CR-M26923). Immunoblot was with an anti Rab7 polyclonal antibody (Cat. No. CR-M21069). |
| Publications: |
| 1. VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors Hepatology Volume 61, Issue 1, pages 361–374, January 2015 |
| 2. Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance Endocrinology. 2014 Sep;155(9):3315-28 |
