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Ca2+ channel agonist 1
  • HY-41076-10mM*1mL
  • MCE
  • 广东省广州市
  • 现货
  • 10mM*1mL瓶
  • 3272
  • 2022-07-23 10:53:35

广州市左克生物科技发展有限公司

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  • CAS号
  • 1402821-24-2

中文名:

SMILES:CC[C@@H](NC1=NC(NCC2=CC=CC=C2)=C3C(N(CCC)C=N3)=N1)CO

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Purity:99.65%

存储条件:Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.

产品详情: Ca2+ channel agonist 1产品活性:Ca2+ channel agonist 1 是一种 N-型钙离子通道 (N-type Ca2+ channel) 激动剂和 Cdk2 的抑制剂,EC50 分别为 14.23 μM 和 3.34 μM,对运动神经终端功能障碍有潜在疗效。产品来源: 研究领域:Membrane Transporter/Ion Channel | Neuronal Signaling | Cell Cycle/DNA Damage作用靶点:作用靶点:Calcium Channel | CDKIn Vitro: Ca2+ channel agonist 1 (Compound 13d) is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively. Ca2+ channel agonist 1 exhibits a ca. 2-fold increased agonism and a 22-fold decreased cdk2 kinase activity versus the standard, (R)-roscovitine.相关产品:Bioactive Compound Library Plus | Cell Cycle/DNA Damage Compound Library | Kinase Inhibitor Library | Membrane Transporter/Ion Channel Compound Library | Neuronal Signaling Compound Library | Anti-Aging Compound Library | Reprogramming Compound Library | Anti-Breast Cancer Compound Library | Anti-Blood Cancer Compound Library | Targeted Diversity Library | Palbociclib | Abemaciclib | Ionomycin | Thapsigargin | L-Ascorbic acid | Ro-3306 | Dinaciclib | Ribociclib | THZ1 | 2-Aminoethyl diphenylborinate | THZ531 | Flavopiridol | Ebselen | Seliciclib | Verapamil hydrochloride | AZD4573 | Acetylcholine chloride | SR-4835 | Nifedipine | Fasudil Hydrochloride | GSK1016790A | Simurosertib | Fadraciclib | Tetrandrine | NVP-2 | Halofuginone品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物,我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物;10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域;设有专业的实验中心和严格的质控、验证体系;提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告,确保产品的高纯度、高品质;产品的生物活性多经各国客户实验验证;Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果;专业团队跟踪最新的制药及生命科学研究进展,为您提供全球最新的活性化合物;与世界各大制药公司及知名科研机构建立了长期的合作。

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