中文名：二氢异丹参酮I

SMILES:O=C1C2=C(C3=C(C=C2)C(C)=CC=C3)C(C4=C1C(C)CO4)=O

产品官网链接：

Purity：99.52%

存储条件:Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.

产品详情: Dihydroisotanshinone I产品活性：Dihydroisotanshinone I 是丹参中的一种生物活性化合物，可抑制雄激素依赖性和雄激素非依赖性前列腺癌细胞的迁移。Dihydroisotanshinone I 还诱导这些肺癌细胞的凋亡 (apoptosis) 和铁死亡 (ferroptosis)。Dihydroisotanshinone I 还阻断 GPX4 的蛋白表达。产品来源： 研究领域：JAK/STAT Signaling | Stem Cell/Wnt | Apoptosis作用靶点：作用靶点：STAT | Apoptosis | FerroptosisIn Vitro: Dihydroisotanshinone I inhibits the protein expression of p-STAT3 and blocked the translocation of STAT3 into the chromatin, as well as suppressed tumor epithelial–mesenchymal transition (EMT) gene expression.Dihydroisotanshinone I (10-30 μM; 24 huors) has inhibitory effects on the growth of the lung cancer cell lines, A549 cells and H460 cells.Dihydroisotanshinone I (20-30 μM; 24 huors) induces pronounced apoptosis in A549 and H460 cells in a dose-dependent manner.Dihydroisotanshinone I can induce ferroptosis in lung cancer cells.In Vivo: Dihydroisotanshinone I (30 mg/kg; intraperitoneally; every 2 days for 18 days) can inhibit metastasis of A549 cells in the nude mice model without adverse effects on mice.相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Apoptosis Compound Library | Immunology/Inflammation Compound Library | JAK/STAT Compound Library | Kinase Inhibitor Library | Stem Cell Signaling Compound Library | Natural Product Library | Anti-Cancer Compound Library | Anti-Aging Compound Library | Differentiation Inducing Compound Library | Ferroptosis Compound Library | Traditional Chinese Medicine Monomer Library | Anti-Breast Cancer Compound Library | Anti-Lung Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Anti-Blood Cancer Compound Library | Transcription Factor Targeted Library | MG-132 | Ferrostatin-1 | Erastin | Cisplatin | LY294002 | Doxorubicin hydrochloride | Bafilomycin A1 | RSL3 | Y-27632 dihydrochloride | Paclitaxel | Acetylcysteine | Angiotensin II human | Deferoxamine mesylate | Cycloheximide | Tamoxifen | Staurosporine | 2-Deoxy-D-glucose | 5-Fluorouracil | Bortezomib | Sorafenib | SP600125 | Trametinib | Necrostatin-1 | Gemcitabine | Temozolomide | MK-2206 dihydrochloride | Verteporfin | Decitabine | ML385品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

尊敬的老师，麻烦下单前确认好，可联系客服 避免订错，产品非质量问题是不能退换的！