中文名：三磷酸腺苷二钠

SMILES:O[C@@H]([C@H]([C@H](N1C=NC2=C1N=CN=C2N)O3)O)[C@H]3COP(O)(OP(OP([O-])(O)=O)([O-])=O)=O.[Na+].[Na+]

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Purity：≥98.0%

存储条件:4°C, sealed storage, away from moisture

产品详情: ATP disodium salt产品活性：ATP disodium salt (Adenosine 5'-triphosphate disodium salt) 是体内能量储存和代谢的重要物质，为代谢提供能量，同时在细胞中作为辅酶发挥作用。ATP disodium salt 是免疫和炎症中重要的内源性信号分子。产品来源： 研究领域：Metabolic Enzyme/Protease作用靶点：作用靶点：Endogenous MetaboliteIn Vitro: ATP disodium salt (5mM; 1 hour) co-treatment with LPS (1 μg/ml) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.ATP disodium salt (2 mM; 0.5-24 hours) induces secretion of interleukin 1β, KC and MIP-2 from bone marrow derived macrophages (BMDMs) in vitro in a caspase-1 activation-dependent manner.ATP disodium salt stimulats cytokine and chemokine secretion and inflammasome activation directly and indirectly induces in vitro neutrophil chemotaxis.In Vivo: ATP disodium salt (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.ATP disodium salt induces the secretion of IL1β, KC and MIP-2 and neutrophils recruitment in vivo.相关产品：Natural Product Library Plus | Drug Repurposing Compound Library Plus | Clinical Compound Library Plus | Bioactive Compound Library Plus | Rapamycin | 3-Methyladenine | Acetylcysteine | 5-Fluorouracil | ATP | Retinoic acid | AICAR | Hydrocortisone | Estradiol | Docetaxel | Nicotinamide | Melatonin | Isoprenaline hydrochloride | Prostaglandin E2 | Cytarabine | Acetaminophen | Capsaicin | L-Ascorbic acid | β-Nicotinamide mononucleotide | (-)-Epigallocatechin Gallate | Palmitic acid | Luteolin | Nicotinamide riboside chloride | Calcitriol | DHEA | Thymidine | Docosahexaenoic acid | NAD+ | Liothyronine | Arachidonic acid品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

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