膜粘连蛋白5重组兔单抗
Annexin V Recombinant Rabbit mAb
- bsm-52841R
- 北京博奥森
- 北京市
- 现货
- 按需
- 议价
- 2023-10-18 15:50:02
北京博奥森生物技术有限公司
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- 英文名称
- Annexin V Recombinant Rabbit mAb
产品编号
bsm-52841R
产品分类
一抗
产品类型
重组兔单抗、质检1级
英文名称
Annexin V Recombinant Rabbit mAb
中文名称
膜粘连蛋白5重组兔单抗
交叉反应
Human,Mouse,Rat
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human Annexin V
亚型
IgG
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
理论分子量
36kDa
浓度
1mg/ml
储存液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
功能
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
亚基
Monomer. Binds ATRX and EIF5B. Interacts with hepatitis B virus (HBV).
亚细胞定位
Monomer. Binds ATRX and EIF5B. Interacts with hepatitis B virus (HBV).
翻译后修饰
S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex.
疾病
Defects in ANXA5 are associated with susceptibility to pregnancy loss, recurrent, type 3 (RPRGL3) [MIM:614391]. A common complication of pregnancy, resulting in spontaneous abortion before the fetus has reached viability. The term includes all miscarriages from the time of conception until 24 weeks of gestation. Recurrent pregnancy loss is defined as 3 or more consecutive spontaneous abortions.
相似性
Belongs to the annexin family.
Contains 4 annexin repeats.
Contains 4 annexin repeats.
数据库链接
Entrez Gene: 308 Human
Entrez Gene: 11747 Mouse
Omim: 131230 Human
SwissProt: P08758 Human
SwissProt: P48036 Mouse
Unigene: 480653 Human
Unigene: 1620 Mouse
Unigene: 3318 Rat
背景资料
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa. [provided by RefSeq, Jul 2008].
