视黄醇结合蛋白4单克隆抗体
- V6203
- 北京博奥森
- 北京市
- 现货
- 按需
- 议价
- 2023-10-09 15:58:31
北京博奥森生物技术有限公司
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产品编号
V6203
产品分类
一抗
英文名称
RBP4 Mouse mAb
中文名称
视黄醇结合蛋白4单克隆抗体
英文别名
plasma retinol binding protein 4; Plasma retinol-binding proteinv; Plasma retinol-binding protein(1-176); prbp; PRO2222; RBP; RET4_HUMAN; Retinol binding protein 4; retinol binding protein 4 interstitial; Retinol binding protein 4 plasma.
抗体来源
Mouse
免疫原
Recombinant Human RBP4 Protein
亚型
IgG1
纯化方法
affinity purified by Protein A
克隆类型
Monoclonal
理论分子量
21kDa
GeneID
5950
Swiss
P02753
储存液
0.01M PBS(pH7.4)
保存条件
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Subunit
Subcellular Location
Secreted.
DISEASE
Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
Similarity
Belongs to the calycin superfamily. Lipocalin family.
Database links
背景资料
Retinol binding protein 4, also known as RBP4, is a transporter protein for retinol (vitamin A alcohol). RBP4 has a molecular weight of approximately 21 kDa and is encoded by the RBP4 gene in humans. It is mainly, though not exclusively, synthesized in the liver and circulates in the bloodstream bound to retinol in a complex with transthyretin. RBP4 has been a drug target for ophthalmology research due to its role in vision. RBP4 may also be involved in metabolic diseases as suggested by recent studies.
