产品编号: KMP2337
产品名称: Mouse CD86 Protein, Fc Tag
中文名称: 重组小鼠CD86蛋白
中文全称: 重组小鼠T 淋巴细胞活化抗原CD86蛋白
关键词: T 淋巴细胞活化抗原 CD86, T-lymphocyte activation antigen CD86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1, CD86, Mouse CD86 Protein, Fc Tag, Recombinant Protein, KMP2337

物种: Mouse
宿主: HEK293 Cells
规格: 50ug, 100ug, 200ug
纯化方式: Affinity purification
纯度: >95% as determined by SDS-PAGE
内毒素水平: <1.0 EU/ug determined by the LAL method
缓冲体系: PBS, pH7.4
Uniprot: Q91YV7
SDS-PAGE: KMP2337 SDS-PAGE image1.png
功能:
产品背景: T-lymphocyte activation antigen CD86(B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. Mouse CD86 shares 59% and 81% aa sequence identity with human and rat CD86, respectively. It contains 1 Ig-like C2-type domainand 1 Ig-like V-type domain. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.
保存条件: Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
运输条件: In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
说明: This product is for research use only.
官网链接: https://www.kmdbioscience.cn/
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