Sample:
Heart (Mouse) Lysate at 40 ug
Lung (Rat) Lysate at 40 ug
Primary: Anti-TFPI (bs-2535R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kD
Observed band size: 52 kD
组织因子途径抑制剂抗体
TFPI Rabbit pAb
- bs-2535R
- 北京博奥森
- 北京市
- 现货
- 50ul
- 100ul
- 200ul
- 议价
- 2023-10-10 14:18:33
北京博奥森生物技术有限公司
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- 英文名称
- TFPI Rabbit pAb
产品编号
bs-2535R
产品分类
一抗
英文名称
TFPI Rabbit pAb
中文名称
组织因子途径抑制剂抗体
英文别名
Tissue factor pathway inhibitor; Tissue factor pathway inhibitor-1; convertin; EPI; Extrinsic pathway inhibitor; LACI; Lipoprotein associated coagulation inhibitor; TFI; TFPI 1; TFPI1; TFPI1_HUMAN.
交叉反应
Mouse,Rat（predicted：Human,Pig,Cow,Horse,Rabbit）
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human TFPI
蛋白细胞定位
分泌型蛋白
亚型
IgG
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
32kDa
GeneID
7035
Swiss
P10646
浓度
1mg/ml
储存液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Subunit
Subcellular Location
Isoform Alpha: Secreted.
Isoform Beta: Microsome membrane; Lipid-anchor, GPI-anchor.
Isoform Beta: Microsome membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity
Mostly in endothelial cells.
Post-translational modifications
O-glycosylated.
Similarity
Contains 3 BPTI/Kunitz inhibitor domains.
Database links
Entrez Gene: 7035 Human
Entrez Gene: 21788 Mouse
Omim: 152310 Human
SwissProt: P10646 Human
SwissProt: O54819 Mouse
Unigene: 516578 Human
Unigene: 124316 Mouse
Unigene: 447013 Mouse
Unigene: 15795 Rat
背景资料
TFPI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins.
组织因子途径抑制因子(tissue factor pathway in hibitor, TFPI)是组织因子凝血途径的主要抑制因子， 组织因子途径抑制因子在诸如动脉粥样硬化，血管再狭窄，弥漫性血管内凝血DIC等方面，有一定的研究价值。
应用
| 应用 | 推荐稀释比例 |
|---|---|
| ELISA | 1:5000-10000 |
| IF | 1:100-500 |
| IHC-F | 1:100-500 |
| IHC-P | 1:100-500 |
| WB | 1:500-2000 |
图片资料
