Anti Active Rab4 Mouse Monoclonal Antibody
- CR-M26921
- 科博瑞生物
- 湖北省武汉市
- 现货
- 30ul
- 4800 元
- 2024-06-12 16:04:19
科博瑞（武汉）生物科技有限公司
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- 种属
- Mouse
Active Rab4A GTP [CR-M26921]
[30 µL]
| Catalog Number: CR-M26921 |
| Gene Symbol: RAB4 |
|
Description: Anti Active Rab4 Mouse Monoclonal Antibody
|
| Background: Rab4 belongs to the small GTPase Rab family. It interacts with RAB11FIP1, RABEP1, ZFYVE20, RUFY1, SGSM1, SGSM2 and SGSM3. It participates in protein transport and in vesicular traffic. |
| Immunogen: Recombinant full length protein of active Rab4A. |
| Applications: IP, IHC |
| Recommended Dilutions: 1 μg for 1~2 mg total cellular proteins for IP 1:50~100 dilution for IHC |
| Concentration: 1 mg/ml |
| Host: mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti-active Rab4 antibody recognizes active Rab4 from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Immunoprecipitation/Western blot: |
 |
Rab4A activation assay. Purified GST-tagged Rab4A proteins (Cat. #CR-M10130) were immunoprecipitated with the anti active Rab4 monoclonal antibody (Cat. No. CR-M26921) after treated with GDP (lane 1) or GTPγ S(lane 2), and was blotted with anti Rab4A polyclonal antibody (Cat. No. CR-M21067). Input control is shown in the bottom panel. |
| Publications: |
| 1. VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors Hepatology Volume 61, Issue 1, pages 361–374, January 2015 |
| 2. Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance Endocrinology. 2014 Sep;155(9):3315-28 |
