AI-Edigene® BRAF p.V600M 标准品
AI-Edigene® BRAF p.V600M Reference Standard Plus
- CBP10425
- Cobioer
- 上海市
- 一个月内
- 1ug
- 900 元
- 2022-09-15 15:47:19
南京科佰生物科技有限公司
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- 英文名称
- AI-Edigene® BRAF p.V600M Reference Standard Plus
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CBP10425
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| Format | Genomic DNA |
| Description | BRAF, serine/threonine-protein kinase B-raf, is a member of the Raf family of serine/threonine protein kinases, which signals through the MAP kinase pathway to regulate cell proliferation and cell growth (PMID: 24737949, PMID: 29540830). BRAF mutations have been identified in a variety of cancers, including, colorectal (PMID: 30122982), lung (PMID: 29729495), thyroid (PMID: 12970315), and melanoma (PMID: 24737949), and a number of mutations have also been demonstrated to confer drug resistance (PMID: 27478040). |
| Technical Data | |
| DNA Change | c.1798G>A |
| AA Change | p.V600M |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000288602 |
| Cosmic ID | COSM1130 |
| Chr position(GRCh37) | chr7:140453137 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |   |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
