Sample:Liver(Mouse) Lysate at 30 ug
Primary: Anti-Neurogenin3 (bs-0922R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 23 kD
Observed band size: 26 kD
神经元素3抗体
Neurogenin3 Rabbit pAb
- bs-0922R
- 北京博奥森
- 北京市
- 现货
- 按需
- 议价
- 2023-10-19 14:55:01
北京博奥森生物技术有限公司
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- 英文名称
- Neurogenin3 Rabbit pAb
概述
产品编号
bs-0922R
产品分类
一抗
英文名称
Neurogenin3 Rabbit pAb
中文名称
神经元素3抗体
英文别名
NGN3; NGN-3; neurogenin 3; Neurog3; Neurogenin-3; ATH4B; Atoh5; Math4B; NEUROG3; ngn3; OTTHUMP00000019730; Protein atonal homolog 5; Class A basic helix-loop-helix protein 7; NGN3_HUMAN.
中文别名
神经营养素-3;
产品应用
IHC-F, ELISA, WB
交叉反应
Mouse,Human（predicted：Sheep,Cow,Dog,Rat）
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human NGN3:61-160/214
亚型
IgG
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
23kDa
浓度
1mg/ml
储存液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
功能
Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types.
亚基
亚细胞定位
Nucleus.
疾病
Defects in NEUROG3 are the cause of diarrhea type 4 (DIAR4) [MIM:610370]. DIAR4 is a characterized by severe, life-threatening watery diarrhea associated with generalized malabsorption and a paucity of enteroendocrine cells.
相似性
Contains 1 basic helix-loop-helix (bHLH) domain.
数据库链接
Entrez Gene: 50674 Human
SwissProt: Q9Y4Z2 Human
背景资料
Neurogenin-3 (NEUROG3) is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine (Wang et al., 2006 [PubMed 16855267]). It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm.
应用
| 应用 | 推荐稀释比例 |
|---|---|
| ELISA | 1:5000-10000 |
| IHC-F | 1:100-500 |
| WB | 1:500-2000 |
图片资料
