| Allergen: |
nAra h 1 (Arachis hypogaea allergen 1)
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| Unit: |
1mg
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| Availability: |
10 Business Day Lead Time
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| Source: |
Blanched peanut, crushed (Runner cultivar)
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| Mol. Wt: |
64.5 kD (monomer)
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| Purification: |
From delipidated peanut extract by affinity chromatography. Purity on silver stained SDS-PAGE >95%.
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| Concentration: |
See product insert.
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| Formulation: |
Preservative and carrier-free in sterile, endotoxin-free,
phosphate buffered saline, pH 7.4
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| Storage: |
Store at -20ºC
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| Notes: |
(1) Upper band is Ara h 1 trimer.
(2) The minor bands below the monomer are Ara h 1 fragments 3.
(3) Avoid repeated Freeze/Thaw cycles.
(4) A LoTox™product, Endotoxin < 0.03 EU/µg.
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| PDB: |
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| Product Resources: |
LoTox™ Natural Ara h 1 Certificate of Analysis
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Allergens are provided for research and commercial use in vitro: Not for human in vivo or therapeutic use.
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References:
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Burks AW, Williams LW, Helm RM, Connaughton C, Cockrell G, O'Brien T. Identification of a major peanut allergen, Ara h 1, in patients with atopic dermatitis and positive peanut challenges. J Allergy Clin Immunol 1991; 88(2):172-9.
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Burks AW, Cockrell G, Stanley JS, Helm RM, Bannon GA. Recombinant peanut allergen Ara h 1 expression and IgE binding in patients with peanut hypersensitivity. J Clin Invest 1995; 96(4):1715-21.
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Maleki SJ, Kopper RA, Shin D, Park CW, Compadre CM, Sampson H, Burks AW, Bannon GA. Structure of the major peanut allergen Ara h 1 may protect IgE-Binding epitopes from degradation. J Immunol 2000; 164:5844-5849.
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Pomés A, Helm RM, Bannon G, Burks AW, Chapman MD. Monitoring peanut allergen in food products by measuring Ara h 1. J Allergy Clin Immunol 2003; 111(3):640-645.
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