Rap1 活性检测试剂盒文献推荐及技术更新
活性G蛋白检测试剂盒是基于特异性识别与 GTP 结合的,而不认识 GDP 结合的GTP酶的单克隆抗体。鉴于单克隆抗体对GTP酶的高亲和力，可以在短时间内进行活化测定。该试剂盒提供了具有高度灵敏性和可靠性。
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01. EPAC Regulates Melanoma Growth by Stimulating mTORC1 Signaling and Loss of EPAC Signaling Dependence Correlates with Melanoma Progression |
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02. Rap1 Activity Is Essential for Focal Adhesion and Slit Diaphragm Integrity |
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03. Actin-binding protein, IQGAP1, regulates LPS-induced RPMVECs hyperpermeability and ICAM-1 upregulation via Rap1/Src signalling pathway |
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04. Active Rap1-mediated inhibition of choroidal neovascularization requires interactions with IQGAP1 in choroidal endothelial cells |
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05. Natural Killer Cell Transcript 4 promotes the development of Sjögren’s Syndrome via activation of Rap1 on B cells |
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06. Activation of the Small GTPase Rap1 Inhibits Choroidal Neovascularization by Regulating Cell Junctions and ROS Generation in Rats |
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07. Developmental stage-dependent regulation of spine formation by calcium-calmodulin-dependent protein kinase IIa and Rap1 |
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08. Opposing effects of actin signaling and LFA-1 on establishing the affinity threshold for inducing effector T-cell responses in mice |
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09. Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization |
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10. cAMP and EPAC Signaling Functionally Replace OCT4 During Induced Pluripotent Stem Cell Reprogramming |
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11. Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization |
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12. Opposing HDAC4 nuclear fluxes due to phosphorylation by ß-adrenergic activated protein kinase A or by activity or Epac activated CaMKII in skeletal muscle fibres |
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13. Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo |
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